.png)
Diabetes and Obesity
SciFed Journal of Obesity Research is an international online peer- reviewed, it is mainly focus on diabetes, BMI, bariatric surgery, overweight, fat etc.
Obesity can occur during infancy, before puberty, in middle-age and in old-age. Obesity can be enviable, comical and pitiable. It can be due to poor economic and socio-logical physiological and psychological factors.2.1 billion people or 30% of global populations are obese or overweight. Nearly half the world population will be overweight or obese by the year 2030.Obesity is defined as an abnormal growth of adipose tissue due to an enlargement of fat cell size (hypertrophic obesity) or increase in fat cell number (hyperplasic obesity) or a combination of both. A body mass index of 30 or more in males and 28.6 or more in female is obesity. Overweight is defined as weight in excess of the average for a given sex, height and age. Overweight is usually due to obesity but can arise from other causes an as abnormal muscle development or fluid retention. 10% increase of weight above normal is considered overweight and over 20% excess of weight above normal is considered to be obese.
Links between Obesity and Type 2 Diabetes
While the exact causes of diabetes are still not fully understood, it is known that factors up the risk of developing different types of diabetes mellitus. For type 2 diabetes, this includes being overweight or obese (having a body mass index - BMI - of 30 or greater).
In fact, obesity is believed to account for 80-85% of the risk of developing type 2 diabetes, while recent research suggests that obese people are up to 80 times more likely to develop type 2 diabetes than those with a BMI of less than 22.
How Does Obesity Cause Type 2 Diabetes?
It is a well-known fact that if you are overweight or obese, you are at greater risk of developing type 2 diabetes, particularly if you have excess weight around your tummy (abdomen).
Causes of Obesity
Genetic Syndromes Causing Obesity:
Monogenetic disorders
Bardet – Biedl syndrome
Causes
Positive caloric balance
Environmental causes
Anatomic Manifestations
Adipocyte hypertrophy
Ectopic fat deposition in other body organs
Pathophysiological Manifestation
Increased free fatty acid
Increased leptin TNF-α and increased mineral corticoids
Clinical Manifestations
High blood pressure
Low HDL-C
Metabolic syndrome
Fatty liver
Hyperandrogenemia in body
Cancer
The above Article originally got published at SciFed Journal of Obesity Research in 2017, To have a glance please visit: click here
0 comments: